WEB-004Original text reviewed
Gene-expression and adult behaviour findings after embryonic 3.5 GHz exposure
The reported finding
28 differentially expressed genes, metabolic-pathway changes and subtle differences in adult behavioural assays were reported.
Reading it carefully
Modest effects at high estimated SAR. Linked to the earlier larval experiment; not an independent replication and not a test of a standards-specified 5G waveform.
Inside the study
Technology connection
Relevant mobile-frequency experiment; waveform and dose described in this record.
Publication type
Original journal research
Exposure conditions
3.5 GHz; estimated SAR 8.27 W/kg; 6–48 h after fertilisation; temperature maintained around 28°C.
Design & controls
Zebrafish; RNA sequencing at 48 h and behavioural testing after growth to adulthood; sham exposure.
Statistics
See reported finding and original tables; effect sizes not independently recalculated.
Related research & shared cohorts
Same Oregon State programme as WEB-003; methods describe subsampling and follow-up routes.
The protection question raised
Which exposure conditions and biological models reproduce this response, and what would establish its relevance to health?
Source verification
Original methods/results sections reviewed; no independent raw-data or supplement audit.
Where to find the result
Original results/methods sections
Editorial notices
Linked notice fields in retrieved Europe PMC/PubMed records checked 21 October 2026; no correction or retraction surfaced there. Publisher-history and forward-citation screening are not exhaustive.
Funding
National Institute of Environmental Health Sciences 10.13039/100000066 P30 ES030287
Conflicts of interest
Disclosure statement not extracted in this source check; see the original publication.
Original publication
Subham Dasgupta; Connor Leong; Michael T Simonich; Lisa Truong; Huaping Liu; Robyn L Tanguay. Transcriptomic and Long-Term Behavioral Deficits Associated with Developmental 3.5 GHz Radiofrequency Radiation Exposures in Zebrafish. Environmental science & technology letters. 2022. doi:10.1021/acs.estlett.2c00037.