NADPH oxidase as a possible link between fields and oxidative stress

What this paper brings together

A mechanistic synthesis linking cation-channel regulation, NADPH oxidase activation and reactive oxygen production.

The authors’ synthesis or proposal

Reviews a proposed route from EMF-sensitive cation channels to NADPH oxidase activation and oxidative stress, discussing downstream damage to DNA and other cell components.

Reading the connections carefully

Biochemical plausibility and synthesis, not direct proof of the complete exposure-to-disease pathway. Authors call for specific in-vivo radical measurements.

Study records to read alongside

These are topical connections within this library. A link does not mean the review cited this particular paper or independently confirmed its result.

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• RF-046 Oxidative mitochondrial DNA markers in primary cortical neurons
• RF-005 DNA damage in selected rodent tissues
• RF-016 Different genotoxic responses across human cell types