What this paper brings together
A 2025 synthesis of laboratory and epidemiological literature proposing an ion-channel-to-oxidative-stress pathway for ELF and wireless exposures.
The authors’ synthesis or proposal
Extends the ion forced-oscillation/voltage-gated ion-channel hypothesis to wireless carrier signals and their ELF/ULF modulation, linking disturbed ionic regulation to mitochondrial and enzyme-generated oxidative stress.
Reading the connections carefully
An explanatory proposal built from heterogeneous earlier studies. Authors acknowledge that details connecting ionic perturbations to ROS production need further exploration.
Corrections & discussion
The publisher records an update on 6 June 2025, two days after first publication. Read the current publisher version.
Find related papers
ELF magnetic fields ↗ Radiofrequency ↗ Modulated wireless signals ↗
Study records to read alongside
These are topical connections within this library. A link does not mean the review cited this particular paper or independently confirmed its result.
- RF-006 Reduced sperm function and oxidative DNA damage in vitro
- RF-008 Cell-stage differences plus transient mature-sperm DNA damage and motility loss
- RF-046 Oxidative mitochondrial DNA markers in primary cortical neurons
- RF-005 DNA damage in selected rodent tissues
- RF-016 Different genotoxic responses across human cell types
Original paper
Dimitris J Panagopoulos; Igor Yakymenko; Geoffry N De Iuliis; George P Chrousos. A comprehensive mechanism of biological and health effects of anthropogenic extremely low frequency and wireless communication electromagnetic fields. Frontiers in public health. 2025. doi:10.3389/fpubh.2025.1585441.
Authors: Dimitris J Panagopoulos; Igor Yakymenko; Geoffry N De Iuliis; George P Chrousos