WEB-050Original text reviewed
100 GHz: mitochondrial injury in a cancer-cell model
The reported finding
SCC-7 cells showed mitochondrial dysfunction, increased ROS/calcium and apoptosis-related changes. L-929 cells did not show comparable changes.
Reading it carefully
Cancer-therapy mechanism study, not normal-tissue hazard. Abstract inconsistently describes caspase dependence; results report unchanged caspase-3 activity and discuss an AIF-associated alternative pathway. Temperature/dose reporting limits causal interpretation.
Inside the study
Technology connection
Higher-frequency laboratory biology relevant to investigating proposed future bands; not a test of a final 6G standard.
Publication type
Original journal research
Exposure conditions
100 GHz source; reported output 88 mW, beam diameter 1.5 cm; key assays after 2 h. Output power is not a calibrated cellular absorbed dose.
Design & controls
Mouse SCC-7 squamous carcinoma versus L-929 fibroblasts; viability, microscopy, ROS, calcium, mitochondrial and apoptosis assays.
Statistics
See the original results; effect sizes were not independently recalculated.
Related research & shared cohorts
Related publication records: WEB-049.
The protection question raised
Which exposure conditions reproduce this finding, and what would establish its relevance beyond the experimental model?
Source verification
Original methods/results and interpretation reviewed; raw data and supplements were not independently audited.
Where to find the result
Original methods and results
Editorial notices
Linked Europe PMC/PubMed notice fields checked 21 October 2026; no correction/retraction surfaced for this record. Publisher/citation screening is not exhaustive.
Funding
See original disclosure; funding details were not established in this check.
Conflicts of interest
See original disclosure; no independently verified conflict assessment.
Original publication
Liu Sun; Wenxia Wang; Shuocheng She; Lei Wang; Jinwu Zhao; Pandeng Hou; Mingxia He. Terahertz Waves Trigger Apoptosis in Cutaneous Squamous Cell Carcinoma via Apoptosis-Inducing Factor Mediated Mitochondrial Pathway. Cells. 2026. doi:10.3390/cells15090810.