WEB-016Original text reviewed

Selective stem-cell gene responses to higher-terahertz irradiation

The reported finding

Prolonged broadband exposure altered selected adipogenic/metabolic genes without broad heat-shock-gene activation.

Reading it carefully

Small replicate set; related Los Alamos publications share a research lineage. 2.52/10 THz are well above the 90–300 GHz research track; mechanistic context, not direct 6G evidence.

Inside the study

Technology connection
Higher-terahertz mechanistic context at 2.52/approximately 10 THz, outside the 90–300 GHz research band; not direct 6G evidence.
Publication type
Original journal research
Exposure conditions
Broadband pulses centred near 10 THz, about 1 mW/cm²; 2/9 h protocols. Comparison CW source: 2.52 THz, about 3 mW/cm². Temperature monitored.
Design & controls
Mouse mesenchymal stem-cell cultures; qPCR of selected differentiation and stress-response genes; non-irradiated controls.
Statistics
See reported finding and original tables; effect sizes not independently recalculated.
The protection question raised
Which exposure conditions and biological models reproduce this response, and what would establish its relevance to health?
Source verification
Original methods/results sections reviewed; no independent raw-data or supplement audit.
Where to find the result
Original results/methods sections
Editorial notices
Linked notice fields in retrieved Europe PMC/PubMed records checked 21 October 2026; no correction or retraction surfaced there. Publisher-history and forward-citation screening are not exhaustive.
Funding
Funding statement not extracted in this source check; see the original publication.
Conflicts of interest
Disclosure statement not extracted in this source check; see the original publication.

Original publication

Boian S Alexandrov; Kim Ø Rasmussen; Alan R Bishop; Anny Usheva; Ludmil B Alexandrov; Shou Chong; Yossi Dagon; Layla G Booshehri; Charles H Mielke; M Lisa Phipps; Jennifer S Martinez; Hou-Tong Chen; George Rodriguez. Non-thermal effects of terahertz radiation on gene expression in mouse stem cells. Biomedical optics express. 2011. doi:10.1364/boe.2.002679.