# WEB-015 — Human and mouse neural stem-cell injury under 220 GHz exposure

Why this matters
Comparing human and animal cells can reveal differences in susceptibility. This experiment investigates proliferation, DNA-damage markers and cell death at a precisely identified sub-terahertz frequency.

Id: WEB-015

Author: Wang et al.

Full Authors: Yunxia Wang; Yu Xiong; Man Chen; Fei Liu; Haiyan He; Qinlong Ma; Peng Gao; Guiming Xiang; Liqun Zhang

Year: 2023

Title: The biological effects of terahertz wave radiation-induced injury on neural stem cells

Journal: iScience

Citation: Yunxia Wang; Yu Xiong; Man Chen; Fei Liu; Haiyan He; Qinlong Ma; Peng Gao; Guiming Xiang; Liqun Zhang. The biological effects of terahertz wave radiation-induced injury on neural stem cells. iScience. 2023. doi:10.1016/j.isci.2023.107418.

Doi: 10.1016/j.isci.2023.107418

Pmid: 37771661

Topic: Neural stem-cell susceptibility; Sub-terahertz biological responses

Verification Group: Original text reviewed

Record Role: Original text reviewed

Featured: False

Exposure: 0.22 THz (220 GHz); 25 or 50 mW/cm² for 5 or 10 min; exposure medium controlled at 25°C with temperature monitoring.

Design: Human iPSC-derived and mouse neural stem cells; matched non-irradiated controls; flow cytometry and γH2AX staining.

Finding: Proliferation decreased and apoptosis/DNA-damage signals increased in time/intensity-dependent patterns; human cells were more susceptible under several matched conditions.

Statistics: See reported finding and original tables; effect sizes not independently recalculated.

Boundary: In-vitro susceptibility study with small experimental replication; not human brain exposure or a deployed 6G waveform. Cell conditions and delivered intensity remain essential.

Protection Question: Which exposure conditions and biological models reproduce this response, and what would establish its relevance to health?

Access: Original methods/results sections reviewed; no independent raw-data or supplement audit.

Locator: Original results/methods sections

Notice: Linked notice fields in retrieved Europe PMC/PubMed records checked 21 October 2026; no correction or retraction surfaced there. Publisher-history and forward-citation screening are not exhaustive.

Funding: Funding statement not extracted in this source check; see the original publication.

Conflicts: Disclosure statement not extracted in this source check; see the original publication.

Source Url: https://doi.org/10.1016/j.isci.2023.107418

Retrieval Links: https://doi.org/10.1016/j.isci.2023.107418 | https://pubmed.ncbi.nlm.nih.gov/37771661/ | https://pmc.ncbi.nlm.nih.gov/articles/PMC10523010/

Verification Date: 2026-10-21

Discovery Id: EML-6G-002

Technology Tracks: 6g|millimetre

Technology Connection: Sub-terahertz research relevant to examining proposed future bands; not an experiment using a 6G standard.

Publication Type: Original journal research

Study Setting: Cells / isolated tissue

Browse Categories: brain|cells