# RF-044 — Prenatal 3.5 GHz exposure and delayed testicular endpoints: retrieval lead

Why this matters
A study of prenatal exposure looked for reproductive changes in male rats a year after birth. The abstract's delayed findings make follow-up beyond infancy an important question. Original dose information and an analysis accounting for offspring from the same litter remain essential to interpretation.

Id: RF-044

Author: Dolanbay et al.

Full Authors: Elif Gelenli Dolanbay; Tugay Mert; Gozde Caliskan Bender; Hava Bektas; Unal Uslu; Claudio Enrique Fernandez-Rodriguez; Suleyman Dasdag

Year: 2025

Title: Male Reproductive and Cellular Damage After Prenatal 3.5 GHz Radiation Exposure: One-Year Postnatal Effects

Journal: Annals of the New York Academy of Sciences

Citation: Elif Gelenli Dolanbay; Tugay Mert; Gozde Caliskan Bender; Hava Bektas; Unal Uslu; Claudio Enrique Fernandez-Rodriguez; Suleyman Dasdag. Male Reproductive and Cellular Damage After Prenatal 3.5 GHz Radiation Exposure: One-Year Postnatal Effects. Annals of the New York Academy of Sciences. 2025;1554(1):140-152. doi:10.1111/nyas.70116.

Doi: 10.1111/nyas.70116

Pmid: 41128732

Topic: Developmental reproductive effects

Verification Group: Original abstract verified

Record Role: Original abstract verified

Featured: False

Exposure: 3.5 GHz,2 h/day during full or late gestation; male offspring studied at 12 months. Dosimetry and waveform details absent from retrieved abstract.

Design: Pregnant Wistar Hannover rats in sham, full-gestation and late-gestation groups; animal/litter counts and full methods not retrieved.

Finding: Primary abstract reports altered testicular tubule/epithelium morphology, Johnsen score, sperm morphology, γH2AX, Beclin 1 and TUNEL at 12 months.

Statistics: Abstract states Holm-Bonferroni correction; full-gestation Johnsen score adjusted P=.022 and sperm morphology P=.036. Extremely small tissue-marker P values need experimental-unit audit.

Boundary: Abstract verified only. Dose, blinding, litter nesting and thermal controls unverified. Numerical significance cannot resolve those limits; no central causal use.

Related: Related prenatal research: WEB-051. Shared authors and exposure approach; cohort independence is unverified.

Protection Question: Could prenatal exposure affect reproductive development much later in life? The delayed endpoints are worth examining, but unverified dose, thermal controls and litter structure prevent a central causal inference.

Access: Original publisher abstract, conflict statement and Crossref metadata reviewed. Retrieval lead.

Locator: Abstract and conflict declaration.

Notice: No editorial notice surfaced in the Scite/primary-record checks used for this record; this is not a comprehensive clean-bill certification.

Funding: Not established from retrieved material.

Conflicts: Authors declare no conflicts of interest.

Source Url: https://doi.org/10.1111/nyas.70116

Retrieval Links: https://doi.org/10.1111/nyas.70116 | https://pubmed.ncbi.nlm.nih.gov/41128732/

Verification Date: 2026-10-21

Technology Tracks: 5g