# RF-031 — Pulse-modulated follow-up in a separate institutional programme

Why this matters
This follow-up used pulsed signals and reported different patterns by sex and frequency in how much blood-borne dye entered brain tissue. It helps define more specific experiments on the brain's protective barrier. Dose and temperature details remain unverified, limiting what the findings reveal about relevant exposure conditions.

Id: RF-031

Author: Sırav and Seyhan

Full Authors: Bahriye Sırav; Nesrin Seyhan

Year: 2016

Title: Effects of GSM modulated radio-frequency electromagnetic radiation on permeability of blood-brain barrier in male & female rats

Journal: Journal of Chemical Neuroanatomy

Citation: Sırav B, Seyhan N. Effects of GSM modulated radio-frequency electromagnetic radiation on permeability of blood-brain barrier in male & female rats. J Chem Neuroanat. 2016;75(Pt B):123-127. doi:10.1016/j.jchemneu.2015.12.010. Online 23 December 2015.

Doi: 10.1016/j.jchemneu.2015.12.010

Pmid: 26723545

Topic: Blood-brain barrier; sex-specific responses

Verification Group: Original abstract verified

Record Role: Original abstract verified

Featured: False

Exposure: Pulse-modulated 900 and 1800 MHz, 20 min. Absorbed dose, pulse parameters and temperature measurement not verified; no low-dose or nonthermal claim adopted.

Design: Six groups of young adult male/female Wistar albino rats; injected Evans-blue, quantitative whole-brain assay; group n/masking to verify.

Finding: Original abstract: male whole-brain Evans-blue content rose from 0.08±0.01 mg% control to 0.13±0.03 at 900 MHz and 0.26±0.05 at 1800 MHz (both p<0.01). Female response reported at 900 MHz, but not 1800 MHz. The abstract does not define the ± measure.

Boundary: Original abstract only; not an independent programme from RF-030 or replication of dark-neuron pathology. Absorbed-dose details remain unverified.

Related: Gazi University programme; journal year 2016, online year 2015.

Protection Question: Do frequency, pulse format and sex modify barrier responses? Unverified absorbed-dose and temperature details prevent this abstract-level record from establishing the adequacy of an exposure limit.

Access: Original PubMed abstract and EPA HERO primary citation record

Locator: PMID 26723545 abstract

Notice: Scite metadata checked 20 Oct 2026; no editorial notice returned. Primary bibliographic records and targeted notices were checked where retrievable; no retraction or expression of concern located. This is not certification that no notice exists.

Funding: PubMed lists non-US government support; exact grant/funder unavailable from retrieved original abstract.

Conflicts: Not reported in retrieved abstract.

Source Url: https://doi.org/10.1016/j.jchemneu.2015.12.010

Retrieval Links: https://doi.org/10.1016/j.jchemneu.2015.12.010 | https://pubmed.ncbi.nlm.nih.gov/26723545/ | https://hero.epa.gov/reference/5434739/

Verification Date: 2026-10-20