# RF-027 — Lund time-course follow-up

Why this matters
The blood-brain barrier normally controls what passes from the bloodstream into brain tissue. This follow-up reported leakage and nerve-cell changes at different times after exposure. It makes the timing of tissue examinations important; the abstract alone cannot show which individual exposure levels drove each result.

Id: RF-027

Author: Eberhardt et al.

Full Authors: Jacob L. Eberhardt; Bertil R. R. Persson; Arne E. Brun; Leif G. Salford; Lars O. G. Malmgren

Year: 2008

Title: Blood-brain barrier permeability and nerve cell damage in rat brain 14 and 28 days after exposure to microwaves from GSM mobile phones

Journal: Electromagnetic Biology and Medicine

Citation: Eberhardt JL, Persson BRR, Brun AE, Salford LG, Malmgren LOG. Blood-brain barrier permeability and nerve cell damage in rat brain 14 and 28 days after exposure to microwaves from GSM mobile phones. Electromagn Biol Med. 2008;27(3):215-229. doi:10.1080/15368370802344037.

Doi: 10.1080/15368370802344037

Pmid: 18821198

Topic: Neuropathology and blood-brain barrier

Verification Group: Original abstract verified

Record Role: Original abstract verified

Featured: False

Exposure: Real programmable 900-MHz GSM phone, TEM cells; 2 h; average whole-body SAR 0.12, 1.2, 12 or 120 mW/kg.

Design: 96 non-anesthetized rats exposed or sham-exposed, examined 14 or 28 days later. Exact allocation, masking and dose-specific estimates require full paper.

Finding: Original abstract: after 14 days, albumin extravasation and neuronal albumin uptake increased (Kruskal-Wallis p=0.02 and 0.002); those findings were not increased after 28 days. Dark neurons increased at 28 days (p=0.02); neuronal albumin uptake correlated with damaged neurons at 28 days (Spearman r=0.41, p<0.01).

Boundary: Original abstract verified; full methods/results not obtained. These are global/time-course findings, not proof that every exposure group differed from sham. Same programme as RF-020; not independent corroboration.

Related: Distinct experiment within Lund programme. Do not combine with 48 rats at 7 days (RF-028).

Protection Question: Could the timing of tissue examination explain different barrier and neuronal findings? The abstract supports a time-course question, but dose-specific results and full methods remain unverified.

Access: Scite original abstract and Lund institutional record

Locator: Original abstract; original pages 215-229 not fully audited

Notice: Scite metadata checked 20 Oct 2026; no editorial notice returned. Primary bibliographic records and targeted notices were checked where retrievable; no retraction or expression of concern located. This is not certification that no notice exists.

Funding: Not established from retrieved original abstract.

Conflicts: Not established from retrieved original abstract.

Source Url: https://doi.org/10.1080/15368370802344037

Retrieval Links: https://doi.org/10.1080/15368370802344037 | https://pubmed.ncbi.nlm.nih.gov/18821198/ | https://lup.lub.lu.se/record/1262772

Verification Date: 2026-10-20