# REV-011 — Animal cancer experiments considered together

Collection: Reviews & proposed mechanisms (not an original experiment)

Doi: 10.1016/j.envint.2025.109482

Title: Effects of radiofrequency electromagnetic field exposure on cancer in laboratory animal studies, a systematic review

Authors: Meike Mevissen; Angélique Ducray; Jerrold M Ward; Annette Kopp-Schneider; James P McNamee; Andrew W Wood; Tania M Rivero; Kurt Straif

Date: 2025-04-25

Issueyear: 2025

Why: Long-term animal cancer experiments deserve to be considered together rather than as isolated reports.

Summary: The corrected synthesis includes 51 studies with 10 chronic bioassays and rates evidence of increased male-rat glioma and heart schwannoma as high certainty within its GRADE/OHAT framework.

Limitations: Animal findings do not quantify human risk. Designs and endpoints were too heterogeneous for meta-analysis; most organs showed no or minimal evidence. Use 2026 corrigendum rather than uncorrected study counts.

Scope: A systematic review of laboratory-animal RF cancer studies. The 2026 corrected abstract reports 51 studies and 10 chronic bioassays.

Exposures: Radiofrequency

Journal: Environment international

Heading: Animal cancer experiments considered together

Id: REV-011

Kind: Systematic review

Topics: Cancer; Animal bioassays

Links: https://doi.org/10.1016/j.envint.2025.109482; https://pubmed.ncbi.nlm.nih.gov/40339346/

Author: Mevissen et al.

Access Label: Abstract checked

Source Check: Original PubMed/EPMC metadata and abstract checked; full article not assessed. Linked PubMed/Europe PMC notice records checked on 21 October 2026; this is not a guarantee that every editorial update is indexed.

Notices: Erratum in: Environ Int. 2026 Jul 13:110368. doi: 10.1016/j.envint.2026.110368. Correction checked: The corrected abstract reports 51 studies and 10 chronic bioassays. It retains high-certainty male-rat glioma and heart-schwannoma conclusions; several counts and benchmark doses were corrected.

Notice Urls: https://pubmed.ncbi.nlm.nih.gov/42442967/; https://doi.org/10.1016/j.envint.2026.110368

Citation: Meike Mevissen; Angélique Ducray; Jerrold M Ward; Annette Kopp-Schneider; James P McNamee; Andrew W Wood; Tania M Rivero; Kurt Straif. Effects of radiofrequency electromagnetic field exposure on cancer in laboratory animal studies, a systematic review. Environment international. 2025. doi:10.1016/j.envint.2025.109482.

Related Studies: RF-001; RF-002; RF-014

Url: /reviews/rev-011/

Year: 2025

Record Type: review_or_mechanism

Source Url: https://doi.org/10.1016/j.envint.2025.109482