# IF-001 — Learning and memory endpoints at 7.5 kHz

Why this matters
The higher-exposure mice had difficulty learning and retaining parts of a task in this intermediate-frequency experiment. These functional findings give the assessment a different focus from isolated cell markers. Equipment problems forced a separate high-exposure cohort, so a carefully matched repeat is needed before applying the result to public exposures.

Id: IF-001

Author: Kumari et al.

Full Authors: Kajal Kumari; Hennariikka Koivisto; Matti Viluksela; Kaisa M. A. Paldanius; Mikael Marttinen; Mikko Hiltunen; Jonne Naarala; Heikki Tanila; Jukka Juutilainen

Year: 2017

Title: Behavioral testing of mice exposed to intermediate frequency magnetic fields indicates mild memory impairment

Journal: plos one

Citation: Kumari K, Koivisto H, Viluksela M, Paldanius KMA, Marttinen M, Hiltunen M, Naarala J, Tanila H, Juutilainen J. Behavioral testing of mice exposed to intermediate frequency magnetic fields indicates mild memory impairment. PLOS ONE. 2017;12(12):e0188880. doi:10.1371/journal.pone.0188880.

Doi: 10.1371/journal.pone.0188880

Pmid: 29206232

Topic: Intermediate and static fields

Verification Group: Original text reviewed

Record Role: Original text reviewed

Featured: False

Exposure: 7.5 kHz magnetic field; sham, 12 or 120 microtesla; continuous exposure for five weeks.

Design: 70 male mice: 30 sham and 20 per exposed group.

Finding: The 120-microtesla group showed impaired task acquisition and passive-avoidance retention, with elevated hippocampal TNF-alpha expression.

Boundary: Equipment problems required a separate high-exposure cohort. Many other endpoints were unchanged. The high field exceeded the occupational reference level cited by the authors.

Protection Question: Do the memory and inflammatory findings persist with concurrent comparison groups? The separate high-exposure cohort limits inference, and intermediate-frequency conditions cannot be transferred directly to public RF exposures.

Access: Full indexed article body reviewed

Locator: Materials and methods; Conclusions; supplementary test summary

Notice: Primary PubMed linked-notice record checked 20 Oct 2026; no correction, concern or retraction linked at check. This is not an exhaustive publisher-history certification.

Funding: Not established from retrieved material.

Conflicts: Not established from retrieved material.

Source Url: https://doi.org/10.1371/journal.pone.0188880

Retrieval Links: https://doi.org/10.1371/journal.pone.0188880 | https://pubmed.ncbi.nlm.nih.gov/29206232/

Verification Date: 2026-10-20